Although wheelchair is useful as hardware for moving purposes such as the elderly and disability person, it is not suitable for driving in environments other than flat ground such as steps and ditches, and so there is a problem that the range of activities is limited.In this paper, we propose an add-on type step elevating mechanism and its control
Impact of rinsing in pesticide packaging waste management: Economic and environmental benefits
Pesticides have become dailiness due to inevitable application of these preparations in agricultural activities, with the consequence of generation of large amounts of waste packaging.Impact on the environment and expenses of management of packaging waste can be minimized if the packaging is immediately rinsed after the application of devices and i
A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosisResearch in context
Summary: Background: SOD1 mutations are a significant contributor of familial amyotrophic lateral sclerosis (ALS) cases.SOD1 mutations increase the propensity for the protein to misfold and aggregate into insoluble proteinaceous deposits within motor neurons and neighbouring cells.The small molecule, CuATSM, has repeatedly shown in mouse models to
The PPLD has advantages over conventional regression methods in application to moderately sized genome-wide association studies.
In earlier work, we have developed and evaluated an alternative approach to the analysis of SPEAR GWAS data, based on a statistic called the PPLD.More recently, motivated by a GWAS for genetic modifiers of the X-linked Mendelian disorder Duchenne Muscular Dystrophy (DMD), we adapted the PPLD for application to time-to-event (TE) phenotypes.Because